Ankrd22 Gene Summary [Mouse]
Is expressed in 2-cell stage embryo; eye; and genitourinary system. Orthologous to human ANKRD22 (ankyrin repeat domain 22). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ankrd22 |
| Official Name | ankyrin repeat domain 22 [Source:MGI Symbol;Acc:MGI:1277101] |
| Ensembl ID | ENSMUSG00000024774 |
| Bio databases IDs | |
| Aliases | ankyrin repeat domain 22 |
| Synonyms | 5430429D21Rik, ankyrin repeat domain 22, D19Ertd675e |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ankrd22 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Ankyrin repeats (many copies)
- Ankyrin repeats (3 copies)
- ankyrin repeats
- Ankyrin repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- sepsis
- lung cancer
- ulcerative colitis
- small vessel disease stroke
- late-onset Alzheimer disease
- colorectal carcinomagenesis
- systemic sclerosis
- septic shock
- colorectal mucinous adenocarcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus