Padi1 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity and protein-arginine deiminase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in blastocyst; early embryo; and oocyte. Orthologous to human PADI1 (peptidyl arginine deiminase 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Padi1 |
| Official Name | peptidyl arginine deiminase, type I [Source:MGI Symbol;Acc:MGI:1338893] |
| Ensembl ID | ENSMUSG00000025329 |
| Bio databases IDs | |
| Aliases | peptidyl arginine deiminase, type I |
| Synonyms | HPAD10, PAD1, PDI, PDI1, peptidyl arginine deiminase 1, peptidyl arginine deiminase, type I |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Padi1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-arginine deiminase
- Protein-arginine deiminase (PAD) N-terminal domain
- Cupredoxin superfamily
- Protein-arginine deiminase (PAD)
- calcium ion binding
- enzyme
- protein binding
- Protein-arginine deiminase (PAD) middle domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Padi1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein-arginine deiminase activity
- calcium ion binding