Stap2 Gene Summary [Mouse]
Predicted to enable signaling adaptor activity. Located in plasma membrane. Orthologous to human STAP2 (signal transducing adaptor family member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Stap2 |
| Official Name | signal transducing adaptor family member 2 [Source:MGI Symbol;Acc:MGI:2147039] |
| Ensembl ID | ENSMUSG00000038781 |
| Bio databases IDs | |
| Aliases | signal transducing adaptor family member 2 |
| Synonyms | BKS, signal transducing adaptor family member 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Stap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- pleckstrin Homology binding region
- SH2 like domain
- Src homology 2 (SH2) domain
- protein binding
- Pleckstrin homology-like domain
- proline rich domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- dextran sodium sulfate-induced colitis
- myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
- tumorigenesis
- kidney stones
- experimental autoimmune encephalomyelitis
role in cell
- apoptosis
- activation in
- degradation in
- phosphorylation in
- expression in
- survival
- binding in
- downregulation in
- quantity
- production in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Stap2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- signaling adaptor activity