Zfp711 Gene Summary [Mouse]
Predicted to enable DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 97. Orthologous to human ZNF711 (zinc finger protein 711). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Zfp711 |
| Official Name | zinc finger protein 711 [Source:MGI Symbol;Acc:MGI:3045342] |
| Ensembl ID | ENSMUSG00000025529 |
| Bio databases IDs | |
| Aliases | zinc finger protein 711 |
| Synonyms | 2810409C01RIK, A230078I01Rik, CMPX1, dJ75N13.1, MRX65, MRX97, RGD1562768, XLID97, Zfp711, zinc finger protein 711, ZNF4, ZNF5, ZNF6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp711 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zfx / Zfy transcription activation region
- Zinc finger, C2H2 type
- RNA polymerase II transcription factor activity, sequence-specific DNA binding
- transcription regulator
- zinc ion binding
- nucleic acid binding
- double-stranded DNA binding
- Zinc-finger double domain
- protein binding
- sequence-specific DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hereditary disorder
- x-linked mental retardation type 97
- X-linked complex neurodevelopmental disorder
- small cell lung cancer
- mental retardation
regulates
- DNA promoter
- DNA endogenous promoter
- RNA polymerase II
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp711 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- regulation of gene expression
- positive regulation of transcription from RNA polymerase II promoter
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromatin
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding
- sequence-specific DNA binding
- sequence-specific DNA binding RNA polymerase II transcription factor activity