Phkg1 Gene Summary [Mouse]
Enables phosphorylase kinase activity. Predicted to be involved in glycogen catabolic process; positive regulation of glycogen catabolic process; and signal transduction. Predicted to be part of phosphorylase kinase complex. Predicted to be active in cytoplasm. Is expressed in cerebral cortex; heart; and liver. Orthologous to human PHKG1 (phosphorylase kinase catalytic subunit gamma 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Phkg1 |
| Official Name | phosphorylase kinase gamma 1 [Source:MGI Symbol;Acc:MGI:97579] |
| Ensembl ID | ENSMUSG00000025537 |
| Bio databases IDs | |
| Aliases | phosphorylase kinase gamma 1 |
| Synonyms | PHKG, PHKIN01, phosphorylase kinase catalytic subunit gamma 1, phosphorylase kinase catalytic subunit γ 1, phosphorylase kinase gamma 1, phosphorylase kinase γ 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Phkg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- ATP binding
- enzyme binding
- Protein kinase domain
- Tyrosine kinase, catalytic domain
- phosphorylase kinase
Pathways
Biological processes and signaling networks where the Phkg1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Phkg1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carbohydrate metabolic process
- glycogen biosynthetic process
Cellular Component
Where in the cell the gene product is active
- phosphorylase kinase complex
- cytosol
Molecular Function
What the gene product does at the molecular level
- tau-protein kinase activity
- phosphorylase kinase activity
- ATP binding
- calmodulin binding
- enzyme binding