B3gat2 Gene Summary [Mouse]
Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. Predicted to be involved in carbohydrate biosynthetic process and chondroitin sulfate proteoglycan biosynthetic process. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Barrett's esophagus and schizophrenia. Orthologous to human B3GAT2 (beta-1,3-glucuronyltransferase 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | B3gat2 |
| Official Name | beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) [Source:MGI Symbol;Acc:MGI:2389490] |
| Ensembl ID | ENSMUSG00000026156 |
| Bio databases IDs | |
| Aliases | beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) |
| Synonyms | AF106624, beta-1,3-glucuronyltransferase 2, GLCATS, Udp Glucuronyltransferase S, β-1,3-glucuronyltransferase 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse B3gat2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Glycosyltransferase family 43
- galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
- catalytic domain
- enzyme
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse B3gat2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carbohydrate metabolic process
- chondroitin sulfate proteoglycan biosynthetic process
- carbohydrate biosynthetic process
- protein glycosylation
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity