Arl14ep Gene Summary [Mouse]

Predicted to be located in several cellular components, including cytosol; focal adhesion; and nuclear lumen. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in cerebral cortex ventricular layer; olfactory cortex ventricular layer; olfactory epithelium; and telencephalon ventricular layer. Orthologous to human ARL14EP (ARF like GTPase 14 effector protein). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Arl14ep
Official Name
ADP-ribosylation factor-like 14 effector protein [Source:MGI Symbol;Acc:MGI:1926020]
Ensembl ID
ENSMUSG00000027122
Bio databases IDs NCBI: 212772 Ensembl: ENSMUSG00000027122
Aliases ADP-ribosylation factor-like 14 effector protein
Synonyms 2700007P21Rik, 4930448O08Rik, ADP-ribosylation factor-like 14 effector protein, ARF7EP, ARF like GTPase 14 effector protein, C11orf46, dJ299F11.1, FLJ38968, RGD1311463
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arl14ep often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ARF7 effector protein C-terminus
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • autosomal recessive nonsyndromic mental retardation
regulated by
  • TP63

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • intracellular membrane-bounded organelle
  • focal adhesions
  • Plasma Membrane
  • cytosol
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Arl14ep gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • focal adhesion
  • intracellular membrane-bounded organelle
  • cytosol
  • nucleolus
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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