ARL14EP Gene Summary [Human]
The protein encoded by this gene is an effector protein. It interacts with ADP-ribosylation factor-like 14 [ARL14, also known as ADP-ribosylation factor 7 (ARF7)], beta-actin (ACTB) and actin-based motor protein myosin 1E (MYO1E). ARL14 is a small GTPase; it controls the export of major histocompatibility class II molecules by connecting to the actin network via this effector protein. [provided by RefSeq, Sep 2014]
Details
| Type | Protein Coding |
| Official Symbol | ARL14EP |
| Official Name | ADP ribosylation factor like GTPase 14 effector protein [Source:HGNC Symbol;Acc:HGNC:26798] |
| Ensembl ID | ENSG00000152219 |
| Bio databases IDs | |
| Aliases | ADP ribosylation factor like GTPase 14 effector protein |
| Synonyms | 2700007P21Rik, 4930448O08Rik, ADP-ribosylation factor-like 14 effector protein, ARF7EP, ARF like GTPase 14 effector protein, C11orf46, dJ299F11.1, FLJ38968, RGD1311463 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARL14EP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ARF7 effector protein C-terminus
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- intracellular membrane-bounded organelle
- focal adhesions
- Plasma Membrane
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARL14EP gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- focal adhesion
- intracellular membrane-bounded organelle
- cytosol
- nucleolus
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding