Rpusd2 Gene Summary [Mouse]

Predicted to enable pseudouridine synthase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis and mRNA pseudouridine synthesis. Is expressed in brain; genitourinary system; parathyroid gland; and trachea. Orthologous to human RPUSD2 (RNA pseudouridine synthase domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rpusd2
Official Name
RNA pseudouridylate synthase domain containing 2 [Source:MGI Symbol;Acc:MGI:1918066]
Ensembl ID
ENSMUSG00000027324
Bio databases IDs NCBI: 271842 Ensembl: ENSMUSG00000027324
Aliases RNA pseudouridylate synthase domain containing 2
Synonyms 4921503C21Rik, 9630001E10, C15orf19, C18B11, LOC100911166, PUS9, RGD1306147, RNA pseudouridine synthase domain containing 2, RNA pseudouridylate synthase domain containing 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpusd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PseudoU_synth
  • pseudouridine synthase, RluA family
  • pseudouridine synthase
  • enzyme
  • RNA pseudouridylate synthase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • refractive error
regulated by
  • HeLa cells

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpusd2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mRNA processing
  • enzyme-directed rRNA pseudouridine synthesis

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • pseudouridine synthase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.