Cfap206 Gene Summary [Mouse]

Involved in regulation of cilium beat frequency; regulation of flagellated sperm motility; and sperm axoneme assembly. Located in axoneme and ciliary basal body. Is expressed in several structures, including brain; nasal cavity; pharynx; reproductive system; and respiratory system. Orthologous to human CFAP206 (cilia and flagella associated protein 206). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cfap206
Official Name
cilia and flagella associated protein 206 [Source:MGI Symbol;Acc:MGI:1916579]
Ensembl ID
ENSMUSG00000028294
Bio databases IDs NCBI: 69329 Ensembl: ENSMUSG00000028294
Aliases cilia and flagella associated protein 206
Synonyms 1700003M02Rik, C6orf165, cilia and flagella associated protein 206, dJ382I10.1, RGD1310641
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cfap206 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • domain of unknown function
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hydrocephalus
  • asthenozoospermia
role in cell
  • abnormal morphology
  • formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • motile cilia
  • basal bodies
  • axonemes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cfap206 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • axoneme assembly
  • cilium movement
  • sperm axoneme assembly
  • regulation of cilium beat frequency

Cellular Component

Where in the cell the gene product is active
  • motile cilium
  • radial spoke
  • cilium basal body
  • axoneme

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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