Tmeff1 Gene Summary [Mouse]
Predicted to enable receptor ligand inhibitor activity. Involved in host-mediated suppression of symbiont invasion. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; ganglia; genitourinary system; and sensory organ. Orthologous to several human genes including TMEFF1 (transmembrane protein with EGF like and two follistatin like domains 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmeff1 |
| Official Name | transmembrane protein with EGF-like and two follistatin-like domains 1 [Source:MGI Symbol;Acc:MGI:1926810] |
| Ensembl ID | ENSMUSG00000028347 |
| Bio databases IDs | |
| Aliases | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| Synonyms | A830033E11, C9orf2, CT120.1, H7365, M7365, TOMOREGULIN, TR-1, transmembrane protein with EGF-like and two follistatin-like domains 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmeff1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- KAZAL_FS
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmeff1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- plasma membrane