TMEFF1 Gene Summary [Human]

Predicted to enable signaling receptor binding activity. Predicted to be involved in animal organ morphogenesis; neuron projection development; and tissue development. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TMEFF1
Official Name
transmembrane protein with EGF like and two follistatin like domains 1 [Source:HGNC Symbol;Acc:HGNC:11866]
Ensembl ID
ENSG00000241697
Bio databases IDs NCBI: 8577 Ensembl: ENSG00000241697
Aliases transmembrane protein with EGF like and two follistatin like domains 1, tomoregulin-1, cancer/testis antigen family 120, member 1
Synonyms A830033E11, C9orf2, CT120.1, H7365, M7365, TOMOREGULIN, TR-1, transmembrane protein with EGF-like and two follistatin-like domains 1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEFF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • KAZAL_FS

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
  • varicocele
regulated by
role in cell
  • growth
  • transition

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMEFF1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.