Spink4 Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. Is expressed in brain ventricular layer; ganglia; liver lobe; and olfactory epithelium. Orthologous to human SPINK4 (serine peptidase inhibitor Kazal type 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spink4 |
| Official Name | serine peptidase inhibitor, Kazal type 4 [Source:MGI Symbol;Acc:MGI:1341848] |
| Ensembl ID | ENSMUSG00000028415 |
| Bio databases IDs | |
| Aliases | serine peptidase inhibitor, Kazal type 4 |
| Synonyms | HEL136, MPGC60, PEC-60, serine peptidase inhibitor Kazal type 4, serine peptidase inhibitor, Kazal type 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spink4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- serine protease inhibitor activity
- protein binding
- KAZAL_FS
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spink4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase inhibitor activity
- protein binding