Nol6 Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing; ribosomal small subunit biogenesis; and tRNA export from nucleus. Located in condensed nuclear chromosome and nucleolus. Is expressed in several structures, including cerebral cortex; gut; liver; spleen; and testis. Orthologous to human NOL6 (nucleolar protein 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nol6 |
| Official Name | nucleolar protein family 6 (RNA-associated) [Source:MGI Symbol;Acc:MGI:2140151] |
| Ensembl ID | ENSMUSG00000028430 |
| Bio databases IDs | |
| Aliases | nucleolar protein family 6 (RNA-associated) |
| Synonyms | AA410091, bA311H10.1, NP6, NRAP, nucleolar protein 6, nucleolar protein family 6 (RNA-associated), UTP22 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nol6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nrap protein domain 1
- Nrap protein nucleotidyltransferase domain 4
- Nrap protein PAP/OAS1-like domain 5
- Nrap protein PAP/OAS-like domain
- Nrap protein domain 6
- protein binding
- Nrap protein domain 3
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- Mitochondria
- chromosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nol6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal small subunit biogenesis
- tRNA export from nucleus
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- mitochondrion
- UTP-C complex
- nucleolus
- nucleoplasm
- condensed nuclear chromosome
- CURI complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding