Enho Gene Summary [Mouse]

Enables hormone activity. Acts upstream of or within positive regulation of Notch signaling pathway. Located in plasma membrane. Is expressed in ductus deferens; epididymis; esophagus; ileum; and prostate gland. Orthologous to human ENHO (energy homeostasis associated). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Enho
Official Name
energy homeostasis associated [Source:MGI Symbol;Acc:MGI:1916888]
Ensembl ID
ENSMUSG00000028445
Bio databases IDs NCBI: 69638 Ensembl: ENSMUSG00000028445
Aliases energy homeostasis associated
Synonyms 1110065P19Rik, 2310040A07Rik, C9orf165, energy homeostasis associated, LOC100042420, RGD1565232, UNQ470
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Enho often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • hormone
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • musashi
disease
  • neoplasia
  • hepatic steatosis
  • metabolic syndrome X
  • weight gain
  • atherosclerosis
  • insulin resistance
regulated by
regulates
  • AKT
  • CREB
  • reactive oxygen species
  • JNK
  • Nalp3 inflammasome
  • CDH5
  • PECAM1
  • G6PC1
  • ACTA2
  • SMAD2/3
role in cell
  • expression in
  • activation in
  • production in
  • generation in
  • phosphorylation in
  • number
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Enho gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction
  • positive regulation of Notch signaling pathway

Cellular Component

Where in the cell the gene product is active
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • hormone activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.