B4galt2 Gene Summary [Mouse]
Predicted to enable galactosyltransferase activity. Acts upstream of or within cerebellar Purkinje cell layer development; learning or memory; and locomotory behavior. Predicted to be located in nucleoplasm. Predicted to be active in Golgi apparatus. Is expressed in early conceptus; eye; gonad; and nervous system. Orthologous to human B4GALT2 (beta-1,4-galactosyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | B4galt2 |
| Official Name | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 [Source:MGI Symbol;Acc:MGI:1858493] |
| Ensembl ID | ENSMUSG00000028541 |
| Bio databases IDs | |
| Aliases | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| Synonyms | B4Gal-T3, beta-1,4-galactosyltransferase 2, beta4Gal-T2, Ggtb2, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2, UDP-Gal:betaGlcNAc β 1,4- galactosyltransferase, polypeptide 2, β-1,4-galactosyltransferase 2, β-1,4-galt 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse B4galt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
- galactosyltransferase
- N-terminal domain of galactosyltransferase
- N-terminal region of glycosyl transferase group 7
- enzyme
- protein binding
- N-acetyllactosamine synthase
- glycosyltransferase family A
- lactose synthase
- Golgi lumenal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- cellular membrane
- Golgi Apparatus
- Golgi membrane
- nucleoplasm
- trans Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse B4galt2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycosylation
- carbohydrate metabolic process
- cerebellar Purkinje cell layer development
- locomotory behavior
- protein glycosylation
- visual learning
- memory
Cellular Component
Where in the cell the gene product is active
- Golgi cisterna membrane
- intracellular membrane-bounded organelle
- Golgi apparatus
- Golgi membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
- metal ion binding
- N-acetyllactosamine synthase activity
- lactose synthase activity
- galactosyltransferase activity