Lrrc41 Gene Summary [Mouse]
Enables identical protein binding activity. Predicted to be involved in protein ubiquitination. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system and retina. Orthologous to human LRRC41 (leucine rich repeat containing 41). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lrrc41 |
| Official Name | leucine rich repeat containing 41 [Source:MGI Symbol;Acc:MGI:2441984] |
| Ensembl ID | ENSMUSG00000028703 |
| Bio databases IDs | |
| Aliases | leucine rich repeat containing 41 |
| Synonyms | D630045E04Rik, D730026A16Rik, leucine rich repeat containing 41, MUF1, PP7759, RGD1311221 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrrc41 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SOCS box
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- hepatocellular carcinoma
- liver cancer
- organismal death
- Klinefelter syndrome
- diethylnitrosamine-induced hepatocellular carcinoma
- diethylnitrosamine-induced liver tumorigenesis
- Turner syndrome
role in cell
- JG-231 sensitivity
- pladienolide B sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lrrc41 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding