Enoph1 Gene Summary [Mouse]

Predicted to enable acireductone synthase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; midbrain; respiratory system; and telencephalon. Orthologous to human ENOPH1 (enolase-phosphatase 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Enoph1
Official Name
enolase-phosphatase 1 [Source:MGI Symbol;Acc:MGI:1915120]
Ensembl ID
ENSMUSG00000029326
Bio databases IDs NCBI: 67870 Ensembl: ENSMUSG00000029326
Aliases enolase-phosphatase 1
Synonyms 2310057D15Rik, BB183658, E1, E-1 ENZYME, enolase-phosphatase 1, MASA, MST145, mtnC, RGD1309016
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Enoph1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • HAD hydrolase, family IA, variant 1
  • acireductone synthase
  • enzyme
  • protein binding
  • 2,3-diketo-5-methylthio-1-phosphopentane phosphatase
  • Haloacid Dehalogenase-like Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • L-methionine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Enoph1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • L-methionine salvage from methylthioadenosine
  • L-methionine biosynthetic process from S-adenosylmethionine

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • magnesium ion binding
  • 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
  • 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
  • protein binding
  • acireductone synthase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.