Sfswap Gene Summary [Mouse]
Predicted to enable RNA binding activity. Acts upstream of or within alternative mRNA splicing, via spliceosome and mRNA 5'-splice site recognition. Predicted to be located in nucleus. Is expressed in central nervous system and retina. Orthologous to human SFSWAP (splicing factor SWAP). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sfswap |
| Official Name | splicing factor SWAP [Source:MGI Symbol;Acc:MGI:101760] |
| Ensembl ID | ENSMUSG00000029439 |
| Bio databases IDs | |
| Aliases | splicing factor SWAP |
| Synonyms | 1190005N23RIK, 6330437E22RIK, AI197402, AW212079, SFRS8, splicing factor SWAP, Srsf8, SWAP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sfswap often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- arginine serine dipeptide repeat domain
- Alternative splicing regulator
- Surp module
- protein binding
- Suppressor-of-White-APricot splicing regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sfswap gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA 5'-splice site recognition
- negative regulation of nuclear mRNA splicing, via spliceosome
- alternative nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding