Capn13 Gene Summary [Mouse]

Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Orthologous to human CAPN13 (calpain 13). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Capn13
Official Name
calpain 13 [Source:MGI Symbol;Acc:MGI:2685789]
Ensembl ID
ENSMUSG00000043705
Bio databases IDs NCBI: 381122 Ensembl: ENSMUSG00000043705
Aliases calpain 13
Synonyms calpain 13, CANP 13, Gm943
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Capn13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • The penta-EF hand (PEF) family
  • Calpain family cysteine protease
  • Calpain_III
  • CysPc

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • carcinoma in situ
  • epithelial cancer in situ
  • ulcerative colitis
regulated by
  • dsHIC1-2998
  • ERG
  • beta-estradiol
  • SND1
role in cell
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Capn13 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • calcium-dependent cysteine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

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