Tmem168 Gene Summary [Mouse]
Predicted to enable sodium channel regulator activity. Acts upstream of or within regulation of ubiquitin-dependent protein catabolic process and regulation of voltage-gated sodium channel activity. Located in nuclear membrane. Is expressed in cerebral cortex ventricular layer and heart ventricle. Orthologous to human TMEM168 (transmembrane protein 168). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem168 |
| Official Name | transmembrane protein 168 [Source:MGI Symbol;Acc:MGI:1921794] |
| Ensembl ID | ENSMUSG00000029569 |
| Bio databases IDs | |
| Aliases | transmembrane protein 168 |
| Synonyms | 5730526F17Rik, 8430437G11Rik, RGD1307778, transmembrane protein 168 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem168 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- sodium channel regulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- nuclear envelope
- transport vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem168 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- transport vesicle
Molecular Function
What the gene product does at the molecular level
- sodium channel regulator activity