Trmt6 Gene Summary [Mouse]

Predicted to be involved in mRNA processing. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus. Is expressed in brain ventricular layer; cerebral cortex subventricular zone; olfactory epithelium; submandibular gland primordium; and thymus primordium. Orthologous to human TRMT6 (tRNA methyltransferase 6 non-catalytic subunit). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Trmt6
Official Name
tRNA methyltransferase 6 [Source:MGI Symbol;Acc:MGI:1914176]
Ensembl ID
ENSMUSG00000037376
Bio databases IDs NCBI: 66926 Ensembl: ENSMUSG00000037376
Aliases tRNA methyltransferase 6
Synonyms 3300001M20Rik, CGI-09, GCD10, Gcd10p, MGC5029, mKIAA1153, RGD1308877, TRM6, tRNA methyltransferase 6, tRNA methyltransferase 6 non-catalytic subunit
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trmt6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Gcd10p family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • hepatocellular carcinoma
  • liver cancer
  • productive infection by HIV-1
regulates
role in cell
  • expression in
  • growth
  • activation in
  • cell death
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Trmt6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mRNA processing
  • tRNA methylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • tRNA (m1A) methyltransferase complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.