Cpsf4 Gene Summary [Mouse]
Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in several structures, including genitourinary system; nervous system; olfactory epithelium; submandibular gland primordium; and vibrissa. Orthologous to human CPSF4 (cleavage and polyadenylation specific factor 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cpsf4 |
| Official Name | cleavage and polyadenylation specific factor 4 [Source:MGI Symbol;Acc:MGI:1861602] |
| Ensembl ID | ENSMUSG00000029625 |
| Bio databases IDs | |
| Aliases | cleavage and polyadenylation specific factor 4 |
| Synonyms | cleavage and polyadenylation specific factor 4, CPSF30, CPSF4 30KD, NAR, NEB-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cpsf4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger
- Zinc-finger containing family
- double-stranded DNA binding
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- zinc finger domain
- sequence-specific DNA binding
Pathways
Biological processes and signaling networks where the Cpsf4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- nucleoplasm
- interchromatin granule clusters
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cpsf4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- mRNA cleavage and polyadenylation specificity factor complex
- intracellular membrane-bounded organelle
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- RNA binding