Npvf Gene Summary [Mouse]
Predicted to enable signaling receptor binding activity. Predicted to be involved in negative regulation of gonadotropin secretion and neuropeptide signaling pathway. Predicted to be located in extracellular region. Is expressed in brain; cerebral cortex; dorsomedial hypothalamic nucleus; hypothalamus; and hypothalamus mantle layer. Orthologous to human NPVF (neuropeptide VF precursor). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Npvf |
| Official Name | neuropeptide VF precursor [Source:MGI Symbol;Acc:MGI:1926488] |
| Ensembl ID | ENSMUSG00000029831 |
| Bio databases IDs | |
| Aliases | neuropeptide VF precursor |
| Synonyms | C7orf9, neuropeptide VF precursor, RFRP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Npvf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- receptor agonist activity
- protein binding
- receptor binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- membrane fraction
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Npvf gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- negative regulation of gonadotropin secretion
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- receptor binding