Slc13a4 Gene Summary [Mouse]

Predicted to enable sodium:sulfate symporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in plasma membrane. Is expressed in several structures, including brain meninges; choroid plexus; decidua; extraembryonic component; and lung. Orthologous to human SLC13A4 (solute carrier family 13 member 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc13a4
Official Name
solute carrier family 13 (sodium/sulfate symporters), member 4 [Source:MGI Symbol;Acc:MGI:2442367]
Ensembl ID
ENSMUSG00000029843
Bio databases IDs NCBI: 243755 Ensembl: ENSMUSG00000029843
Aliases solute carrier family 13 (sodium/sulfate symporters), member 4
Synonyms 9630060C05Rik, NAS2, solute carrier family 13 member 4, solute carrier family 13 (sodium/sulfate symporters), member 4, solute carrier family 13 (sodium/sulphate symporters), member 4, SUT-1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc13a4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • sodium:sulfate symporter
  • ArsB_NhaD_permease
  • protein binding
  • transporter
  • citrate transporter
  • anion transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • nonalcoholic steatohepatitis
  • plantar wart
  • juvenile rheumatoid arthritis
regulated by
  • beta-estradiol
  • ESR1
  • PD173074
  • A-83-01
  • BMP4
  • CX3CR1
  • estradiol-17beta-benzoate
regulates
  • sulfate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc13a4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sulfate transport
  • transmembrane transport
  • sodium ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • transmembrane transporter activity
  • sodium:sulfate symporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.