Eogt

Enables protein O-acetylglucosaminyltransferase activity. Involved in protein O-linked glycosylation. Predicted to be active in endoplasmic reticulum lumen. Is expressed in several structures, including blood vessel; central nervous system; limb; lung; and tail unsegmented mesenchyme. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human EOGT (EGF domain specific O-linked N-acetylglucosamine transferase). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Eogt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Eogt gene, providing context for its role in the cell.