Fam3a Gene Summary [Mouse]

Predicted to enable carbohydrate binding activity. Acts upstream of or within several processes, including ATP biosynthetic process; insulin secretion; and response to glucose. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human FAM3A (FAM3 metabolism regulating signaling molecule A). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fam3a
Official Name
family with sequence similarity 3, member A [Source:MGI Symbol;Acc:MGI:1913544]
Ensembl ID
ENSMUSG00000031399
Bio databases IDs NCBI: 66294 Ensembl: ENSMUSG00000031399
Aliases family with sequence similarity 3, member A
Synonyms 1810037C20RIK, 2-19, 2.19, DLD, DXS560S, FAM3 metabolism regulating signaling molecule A, RGD1562076, XAP-7
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Interleukin-like EMT inducer
  • Domains similar to the Pancreatic-derived factor

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • impaired glucose tolerance
  • angiotensin II-induced abdominal aortic aneurysm
  • abdominal aortic aneurysm
regulated by
  • AR
  • rosiglitazone
  • ALOX5
  • levodopa
  • polycystin
  • Influenza A virus (A/Bangkok/RX73(H3N2))
regulates
role in cell
  • expression in
  • organization
  • binding in
  • ubiquitination in
  • transcription in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam3a gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • antifungal humoral response

Cellular Component

Where in the cell the gene product is active
  • extracellular space

Molecular Function

What the gene product does at the molecular level
  • carbohydrate binding