Fam3a Gene Summary [Rat]
Predicted to enable carbohydrate binding activity. Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide and negative regulation of antifungal innate immune response. Predicted to act upstream of or within several processes, including ATP biosynthetic process; insulin secretion; and response to glucose. Predicted to be located in membrane. Predicted to be active in extracellular space. Orthologous to human FAM3A (FAM3 metabolism regulating signaling molecule A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam3a |
| Official Name | family with sequence similarity 3, member A [Source:RGD Symbol;Acc:1562076] |
| Ensembl ID | ENSRNOG00000060623 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 3, member A |
| Synonyms | 1810037C20RIK, 2-19, 2.19, DLD, DXS560S, FAM3 metabolism regulating signaling molecule A, RGD1562076, XAP-7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fam3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Interleukin-like EMT inducer
- Domains similar to the Pancreatic-derived factor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- impaired glucose tolerance
- angiotensin II-induced abdominal aortic aneurysm
- abdominal aortic aneurysm
role in cell
- expression in
- organization
- binding in
- ubiquitination in
- transcription in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fam3a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- antifungal humoral response
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- carbohydrate binding