Coil Gene Summary [Mouse]
Enables disulfide oxidoreductase activity. Predicted to be involved in spliceosomal snRNP assembly. Located in Cajal body and female germ cell nucleus. Is expressed in brain; dorsal grey horn; and early conceptus. Orthologous to human COIL (coilin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Coil |
| Official Name | coilin [Source:MGI Symbol;Acc:MGI:104842] |
| Ensembl ID | ENSMUSG00000033983 |
| Bio databases IDs | |
| Aliases | coilin |
| Synonyms | CLN80, coilin, p80, p80-coilin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Coil often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- disulfide oxidoreductase
- Coilin N-terminus
- enzyme
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- interchromatin granule cluster fractions
- nuclear fraction
- soluble fraction
- fibrillar center
- Cytoplasm
- cytosol
- perinucleolar rings
- nuclear foci
- nucleoplasm
- nucleoli
- nuclear bodies
- coiled body
- Cajal bodies
- perikaryon
- cytoplasmic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Coil gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spliceosomal snRNP assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- membrane
- Cajal body
- cytosol
- nucleolus
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- U1 snRNA binding
- U2 snRNA binding