U2surp Gene Summary [Mouse]

Predicted to enable RNA binding activity. Predicted to be involved in RNA processing. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in central nervous system and sensory organ. Orthologous to human U2SURP (U2 snRNP associated SURP domain containing). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
U2surp
Official Name
U2 snRNP-associated SURP domain containing [Source:MGI Symbol;Acc:MGI:1915208]
Ensembl ID
ENSMUSG00000032407
Bio databases IDs NCBI: 67958 Ensembl: ENSMUSG00000032407
Aliases U2 snRNP-associated SURP domain containing
Synonyms 2610101N10Rik, AU023006, fSAPa, RGD1307882, SR140, U2 snRNP-associated SURP domain containing
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse U2surp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • cwf21 domain
  • RNA recognition motif
  • VHS, ENTH and ANTH domain superfamily
  • CID domain
  • Surp module
  • protein binding
  • Suppressor-of-White-APricot splicing regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • metabolic syndrome X
  • Hutchinson-Gilford progeria syndrome
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • spliceosomes
  • nucleoplasm
  • interchromatin granule clusters

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse U2surp gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

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