Slc25a36 Gene Summary [Mouse]
Predicted to enable pyrimidine nucleotide transmembrane transporter activity. Predicted to be involved in mitochondrial genome maintenance; pyrimidine nucleotide import into mitochondrion; and regulation of mitochondrial membrane potential. Located in mitochondrion. Is expressed in embryo. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 8. Orthologous to human SLC25A36 (solute carrier family 25 member 36). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc25a36 |
| Official Name | solute carrier family 25, member 36 [Source:MGI Symbol;Acc:MGI:1924909] |
| Ensembl ID | ENSMUSG00000032449 |
| Bio databases IDs | |
| Aliases | solute carrier family 25, member 36 |
| Synonyms | C330005L02Rik, HHF8, PNC2, solute carrier family 25 member 36, solute carrier family 25, member 36 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc25a36 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitochondrial carrier protein
- pyrimidine nucleotide transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc25a36 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of mitochondrial membrane potential
- pyrimidine nucleotide transport
- mitochondrion organization
- mitochondrial genome maintenance
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- pyrimidine nucleotide transmembrane transporter activity