Mrpl3 Gene Summary [Mouse]
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; genitourinary system; liver; lung; and spleen. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 9. Orthologous to human MRPL3 (mitochondrial ribosomal protein L3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrpl3 |
| Official Name | mitochondrial ribosomal protein L3 [Source:MGI Symbol;Acc:MGI:2137204] |
| Ensembl ID | ENSMUSG00000032563 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein L3 |
| Synonyms | 2010320L16Rik, 5930422H18Rik, COXPD9, dcr, L3mt, mitochondrial ribosomal protein L3, MRL3, RPML3, uL3m |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal protein L3
- structural constituent of ribosome
- rpl3p
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
- translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial large ribosomal subunit
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- RNA binding
- structural constituent of ribosome