Kat6a

Enables chromatin binding activity and histone H3K9 acetyltransferase activity. Acts upstream of or within several processes, including circulatory system development; face morphogenesis; and negative regulation of DNA-binding transcription factor activity. Located in nucleus. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; and liver. Used to study DiGeorge syndrome. Human ortholog(s) of this gene implicated in Arboleda-Tham syndrome and acute myeloid leukemia. Orthologous to human KAT6A (lysine acetyltransferase 6A). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kat6a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Kat6a gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Kat6a gene, providing context for its role in the cell.