Armcx1 Gene Summary [Mouse]
Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including central nervous system; dorsal root ganglion; eye; and heart. Orthologous to human ARMCX1 (armadillo repeat containing X-linked 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Armcx1 |
| Official Name | armadillo repeat containing, X-linked 1 [Source:MGI Symbol;Acc:MGI:1925498] |
| Ensembl ID | ENSMUSG00000033460 |
| Bio databases IDs | |
| Aliases | armadillo repeat containing, X-linked 1 |
| Synonyms | 3010033I09Rik, ALEX1, armadillo repeat containing X-linked 1, armadillo repeat containing, X-linked 1, GASP7, LOC108348137 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Armcx1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Armadillo-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- prostatic adenocarcinoma
- prostate cancer
- lung adenocarcinoma
- lung adenocarcinoma formation
- rectal adenocarcinoma
- colorectal carcinomagenesis
- rectum cancer
- urothelial bladder carcinoma
- transitional cell bladder cancer
role in cell
- homeostasis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Armcx1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein binding