Armcx1 Gene Summary [Rat]

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
Armcx1
Official Name
armadillo repeat containing, X-linked 1 [Source:RGD Symbol;Acc:1561629]
Ensembl ID
ENSRNOG00000037709
Bio databases IDs NCBI: 102554790 NCBI: 501619 Ensembl: ENSRNOG00000037709
Aliases armadillo repeat containing, X-linked 1
Synonyms 3010033I09Rik, ALEX1, armadillo repeat containing X-linked 1, armadillo repeat containing, X-linked 1, GASP7, LOC108348137
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Armcx1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Armadillo-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • prostatic adenocarcinoma
  • prostate cancer
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • rectal adenocarcinoma
  • colorectal carcinomagenesis
  • rectum cancer
  • urothelial bladder carcinoma
  • transitional cell bladder cancer
regulated by
role in cell
  • homeostasis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Armcx1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial outer membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.