Myo5c Gene Summary [Mouse]
Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and endocytosis. Predicted to act upstream of or within establishment of secretory granule localization. Predicted to be located in secretory granule. Predicted to be active in actin cytoskeleton; cytoplasm; and membrane. Is expressed in several structures, including gut; liver; respiratory system; sensory organ; and submandibular gland primordium. Orthologous to human MYO5C (myosin VC). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Myo5c |
| Official Name | myosin VC [Source:MGI Symbol;Acc:MGI:2442485] |
| Ensembl ID | ENSMUSG00000033590 |
| Bio databases IDs | |
| Aliases | myosin VC |
| Synonyms | 9130003O20RIK, BB085560, C330029I24, Myo5c predicted, myosin VC |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Myo5c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Putative cell-wall binding lipoprotein
- Autophagy protein 16 (ATG16)
- Synaptonemal complex protein 1 (SCP-1)
- Autophagy protein ATG17-like domain
- K-box region
- Laminin Domain I
- Tropomyosin
- Calmodulin-binding motif
- Myosin-like coiled-coil protein
- Tubulin binding cofactor A
- iSH2_PI3K_IA_R
- HOOK protein coiled-coil region
- Centrosomal protein of 63 kDa
- Family of unknown function (DUF6262)
- DIL domain
- Mitotic checkpoint protein
- SPEC
- Domain of unknown function (DUF4515)
- TPR/MLP1/MLP2-like protein
- Tropomyosin like
- Ezrin/radixin/moesin, alpha-helical domain
- Myosin and Kinesin motor domain
- Hyaluronan mediated motility receptor N-terminal
- Cargo binding domain of myosin 5 and similar proteins
- SWI5-dependent HO expression protein 3
- Calcium binding and coiled-coil domain (CALCOCO1) like
- Myosin head (motor domain)
- IQ calmodulin-binding motif
- Domain of unknown function (DUF4659)
- Alpha helical coiled-coil rod protein (HCR)
- RIM-binding protein of the cytomatrix active zone
- MAP7 (E-MAP-115) family
- Intermediate filament protein
- Septation ring formation regulator, EzrA
- Apolipoprotein A1/A4/E domain
- Myosin
Pathways
Biological processes and signaling networks where the Myo5c gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane tubule
- secretory granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Myo5c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle transport along actin filament
- actin filament organization
Cellular Component
Where in the cell the gene product is active
- myosin complex
- extracellular vesicular exosome
- cytoplasm
- membrane
- actin cytoskeleton
- vesicle
Molecular Function
What the gene product does at the molecular level
- actin filament binding
- ATP binding
- calmodulin binding
- microfilament motor activity