Rxylt1 Gene Summary [Mouse]
Predicted to enable ribitol beta-1,4-xylosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Located in Golgi apparatus. Is expressed in forelimb bud. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A10. Orthologous to human RXYLT1 (ribitol xylosyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rxylt1 |
| Official Name | ribitol xylosyltransferase 1 [Source:MGI Symbol;Acc:MGI:2384919] |
| Ensembl ID | ENSMUSG00000034620 |
| Bio databases IDs | |
| Aliases | ribitol xylosyltransferase 1 |
| Synonyms | 6330415D21Rik, HP10481, MDDGA10, ribitol xylosyltransferase 1, TMEM5, type 2 MEMBRANE |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rxylt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribitol-5-phosphate xylosyltransferase 1, and related proteins
- enzyme
- protein binding
- xylosyltransferase
- UDP-glycosyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Golgi Apparatus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rxylt1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked mannosylation
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
- Golgi apparatus
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding