Chpt1 Gene Summary [Mouse]
Enables phosphotransferase activity, for other substituted phosphate groups. Acts upstream of or within phosphatidylcholine biosynthetic process. Located in Golgi apparatus. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and retina. Orthologous to human CHPT1 (choline phosphotransferase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Chpt1 |
| Official Name | choline phosphotransferase 1 [Source:MGI Symbol;Acc:MGI:2384841] |
| Ensembl ID | ENSMUSG00000060002 |
| Bio databases IDs | |
| Aliases | choline phosphotransferase 1 |
| Synonyms | choline phosphotransferase 1, CPT, CPT1, LOC101928981, LOC101929005, LOC105369940 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Chpt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- substituted phosphate group transferase
- diacylglycerol cholinephosphotransferase
- enzyme
- protein binding
- CDP-alcohol phosphatidyltransferase
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Chpt1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- CDP-choline pathway
- regulation of cell growth
- lipid metabolic process
- platelet activating factor biosynthetic process
- phosphatidylcholine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- intracellular membrane-bounded organelle
- membrane
- Golgi apparatus
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- diacylglycerol cholinephosphotransferase activity
- diacylglycerol binding