Gipc3 Gene Summary [Mouse]

Is expressed in several structures, including gonad; liver; lung; spleen; and submandibular gland. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 15. Orthologous to human GIPC3 (GIPC PDZ domain containing family member 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gipc3
Official Name
GIPC PDZ domain containing family, member 3 [Source:MGI Symbol;Acc:MGI:2387006]
Ensembl ID
ENSMUSG00000034872
Bio databases IDs NCBI: 209047 Ensembl: ENSMUSG00000034872
Aliases GIPC PDZ domain containing family, member 3
Synonyms Ahl5, C19orf64, DFNB15, DFNB72, DFNB95, GIPC PDZ domain containing family member 3, GIPC PDZ domain containing family, member 3, RGD1563255, RGS19IP3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gipc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain present in PSD-95, Dlg, and ZO-1/2
  • GIPC homology 2 (GH2) domain-like family
  • canonical PDZ domain
  • protein binding
  • PDZ domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • autosomal recessive deafness type 15
  • sensorineural hearing loss
  • autosomal recessive deafness
  • familial nonsyndromic hearing impairment
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gipc3 gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.