Klhl9 Gene Summary [Mouse]
Predicted to enable cullin family protein binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination and regulation of cytokinesis. Predicted to be located in midbody. Predicted to be part of Cul3-RING ubiquitin ligase complex. Is expressed in central nervous system; male reproductive system; neural retina; and urinary system. Orthologous to human KLHL9 (kelch like family member 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Klhl9 |
| Official Name | kelch-like 9 [Source:MGI Symbol;Acc:MGI:2180122] |
| Ensembl ID | ENSMUSG00000070923 |
| Bio databases IDs | |
| Aliases | kelch-like 9 |
| Synonyms | 8030469P05, C530050O22RIK, kelch-like 9, kelch-like family member 9, KIAA1354, LOC158014, mKIAA1354, RGD1304814 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Klhl9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Galactose oxidase, central domain
- Kelch motif
- BTB And C-terminal Kelch
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- ubiquitin-protein transferase activity
- BTB/POZ domain
- enzyme
- protein binding
- BACK (BTB and C-terminal Kelch) domain
- Kelch domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- midbody
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Klhl9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- regulation of cytokinesis
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytosol
- Cul3-RING ubiquitin ligase complex
- midbody
Molecular Function
What the gene product does at the molecular level
- ubiquitin-protein ligase activity
- protein binding