Synrg Gene Summary [Mouse]
Predicted to be involved in endocytosis and protein transport. Predicted to be located in several cellular components, including Golgi apparatus; clathrin-coated vesicle; and perinuclear region of cytoplasm. Predicted to be part of clathrin coat of trans-Golgi network vesicle. Is expressed in several structures, including cardiovascular system; gallbladder; genitourinary system; gut; and nervous system. Orthologous to human SYNRG (synergin gamma). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Synrg |
| Official Name | synergin, gamma [Source:MGI Symbol;Acc:MGI:1354742] |
| Ensembl ID | ENSMUSG00000034940 |
| Bio databases IDs | |
| Aliases | synergin, gamma |
| Synonyms | AP1GBP1, synergin gamma, synergin, gamma, synergin γ, synergin, γ, SYNG, γ synergin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Synrg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Eps15 homology domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- Golgi Apparatus
- cytosol
- Golgi membrane
- trans Golgi network
- clathrin-coated vesicles
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Synrg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- intracellular protein transport
- endocytosis
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- cytoplasm
- clathrin coat of trans-Golgi network vesicle
- AP-1 adaptor complex
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding