Ppp1r26 Gene Summary [Mouse]
Predicted to enable protein phosphatase inhibitor activity. Predicted to be located in nucleolus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human PPP1R26 (protein phosphatase 1 regulatory subunit 26). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Ppp1r26 |
| Official Name | protein phosphatase 1, regulatory subunit 26 [Source:MGI Symbol;Acc:MGI:2685193] |
| Ensembl ID | ENSMUSG00000035829 |
| Bio databases IDs | |
| Aliases | protein phosphatase 1, regulatory subunit 26 |
| Synonyms | AABR07051376.1, Gm347, KIAA0649, LOC100364681, LOC687551, mKIAA0649, NRBE3, protein phosphatase 1 regulatory subunit 26, protein phosphatase 1, regulatory subunit 26 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp1r26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein phosphatase 1 regulatory subunit 26 N-terminus
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- liver cancer
- epithelial cancer
- breast cancer
- hepatocellular carcinoma
- schizophrenia
- organismal death
role in cell
- expression in
- accumulation in
- binding in
- degradation in
- epithelial-mesenchymal transition in
- glycolysis in
- ubiquitination in
- G1/S phase transition
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppp1r26 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein phosphatase inhibitor activity
- protein binding