PPP1R26 Gene Summary [Human]
Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of phosphatase activity. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PPP1R26 |
| Official Name | protein phosphatase 1 regulatory subunit 26 [Source:HGNC Symbol;Acc:HGNC:29089] |
| Ensembl ID | ENSG00000196422 |
| Bio databases IDs | |
| Aliases | protein phosphatase 1 regulatory subunit 26, DRIM/UTP20 interacting protein, 1A6/DRIM (down-regulated in metastasis) interacting protein |
| Synonyms | AABR07051376.1, Gm347, KIAA0649, LOC100364681, LOC687551, mKIAA0649, NRBE3, protein phosphatase 1 regulatory subunit 26, protein phosphatase 1, regulatory subunit 26 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PPP1R26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein phosphatase 1 regulatory subunit 26 N-terminus
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- liver cancer
- epithelial cancer
- breast cancer
- hepatocellular carcinoma
- schizophrenia
- organismal death
role in cell
- expression in
- accumulation in
- binding in
- degradation in
- epithelial-mesenchymal transition in
- glycolysis in
- ubiquitination in
- G1/S phase transition
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PPP1R26 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein phosphatase inhibitor activity
- protein binding