Ubac1 Gene Summary [Mouse]

Predicted to enable polyubiquitin modification-dependent protein binding activity and proteasome binding activity. Predicted to be involved in protein maturation and protein ubiquitination. Predicted to be located in Golgi apparatus; cytosol; and plasma membrane. Predicted to be part of ubiquitin ligase complex. Is expressed in several structures, including cranial ganglion; dorsal root ganglion; liver lobe; neural tube; and vibrissa. Orthologous to human UBAC1 (UBA domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ubac1
Official Name
ubiquitin associated domain containing 1 [Source:MGI Symbol;Acc:MGI:1920995]
Ensembl ID
ENSMUSG00000036352
Bio databases IDs NCBI: 98766 Ensembl: ENSMUSG00000036352
Aliases ubiquitin associated domain containing 1
Synonyms 1110033G07Rik, GBDR1, Gdbr1, KPC2, UBADC1, UBA domain containing 1, ubiquitin associated domain containing 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ubac1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UBA domain-like superfamily
  • binding protein
  • Ubl1_cv_Nsp3_N-like
  • protein binding
  • STI1 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
  • uterine leiomyoma
  • leiomyomatosis
  • rheumatoid arthritis
  • lung adenocarcinoma formation
  • lung adenocarcinoma
regulated by
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Plasma Membrane
  • Golgi Apparatus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ubac1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein maturation
  • protein ubiquitination

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • ubiquitin ligase complex
  • cytosol
  • Golgi apparatus
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • proteasome binding
  • polyubiquitin binding

Gene-Specific Assays for Results You Can Trust

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