Mgarp Gene Summary [Mouse]
Involved in several processes, including axonal transport; cellular response to gonadotropin-releasing hormone; and nervous system development. Located in mitochondrial inner membrane and mitochondrial outer membrane. Is expressed in several structures, including adrenal gland; brain; chondrocranium; lens; and retina. Orthologous to human MGARP (mitochondria localized glutamic acid rich protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mgarp |
| Official Name | mitochondria localized glutamic acid rich protein [Source:MGI Symbol;Acc:MGI:1914999] |
| Ensembl ID | ENSMUSG00000037161 |
| Bio databases IDs | |
| Aliases | mitochondria localized glutamic acid rich protein |
| Synonyms | 4930583H14Rik, C4orf49, CESP-1, HUMMR, LOC679386, M3d2, mitochondria-localized glutamic acid-rich protein, OSAP, Qsap |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mgarp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitochondria localization Sequence
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mgarp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein targeting to mitochondrion
- cellular response to steroid hormone stimulus
- negative regulation of dendrite development
- cellular response to gonadotropin-releasing hormone
- anterograde axon cargo transport
- axon transport of mitochondrion
- cellular response to hypoxia
- cerebral cortex development
- regulation of mitochondrion organization
- retrograde axon cargo transport
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial outer membrane
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding