Taf2

Predicted to enable chromatin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in G2/M transition of mitotic cell cycle; positive regulation of transcription initiation by RNA polymerase II; and transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex and transcription factor TFTC complex. Is expressed in tail. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 40. Orthologous to human TAF2 (TATA-box binding protein associated factor 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Taf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Taf2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Taf2 gene, providing context for its role in the cell.