Prpf38a Gene Summary [Mouse]
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of U2-type precatalytic spliceosome. Is expressed in lower jaw incisor; submandibular gland primordium; upper jaw incisor; and vibrissa. Orthologous to human PRPF38A (pre-mRNA processing factor 38A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Prpf38a |
| Official Name | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A [Source:MGI Symbol;Acc:MGI:1916962] |
| Ensembl ID | ENSMUSG00000063800 |
| Bio databases IDs | |
| Aliases | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A |
| Synonyms | 2410002M20, 2410002M20Rik, pre-mRNA processing factor 38A, Prp38, PRP38A, PRP38 pre-mRNA processing factor 38 (yeast) domain containing A, RGD1311129, RPF38A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prpf38a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PRP38 family
- protein binding
Pathways
Biological processes and signaling networks where the Prpf38a gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- interchromatin granule cluster fractions
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prpf38a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- precatalytic spliceosome
- U2-type precatalytic spliceosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding