Nsrp1 Gene Summary [Mouse]
Predicted to enable mRNA binding activity. Acts upstream of or within in utero embryonic development. Predicted to be located in nuclear speck. Predicted to be part of ribonucleoprotein complex. Is expressed in several structures, including compacted morula; immune system; and oocyte. Orthologous to human NSRP1 (nuclear speckle splicing regulatory protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nsrp1 |
| Official Name | nuclear speckle regulatory protein 1 [Source:MGI Symbol;Acc:MGI:2144305] |
| Ensembl ID | ENSMUSG00000037958 |
| Bio databases IDs | |
| Aliases | nuclear speckle regulatory protein 1 |
| Synonyms | 8030451K07, CCDC55, HSPC095, NEDSSBA, NSpr70, NSrp70, nuclear speckle regulatory protein 1, nuclear speckle splicing regulatory protein 1, RGD1309863 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nsrp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA binding
- Nuclear speckle splicing regulatory protein 1, N-terminal
- protein binding
- Nuclear speckle splicing regulatory protein 1, RS-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neurodevelopmental disorder with spasticity, seizures, and brain abnormalities
- metastasis
- organismal death
role in cell
- phosphorylation in
- degradation in
- expression in
- migration
- invasion by
- alternative splicing by
- alternative splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nsrp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- in utero embryonic development
- regulation of alternative nuclear mRNA splicing, via spliceosome
- mRNA processing
- developmental process
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- mRNA binding