Ddx60 Gene Summary [Mouse]
Enables RNA binding activity. Acts upstream of or within defense response to virus. Located in cytoplasm. Is expressed in lens. Orthologous to human DDX60 (DExD/H-box helicase 60). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ddx60 |
| Official Name | DExD/H box helicase 60 [Source:MGI Symbol;Acc:MGI:2384570] |
| Ensembl ID | ENSMUSG00000037921 |
| Bio databases IDs | |
| Aliases | DExD/H box helicase 60 |
| Synonyms | 9830118M07, BC013672, DExD/H box helicase 60 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ddx60 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- double-stranded DNA binding
- helicase superfamily c-terminal domain
- double-stranded RNA binding
- DEAD/DEAH box helicase
- Type III restriction enzyme, res subunit
- N-terminal helicase domain of the DEAD-box helicase superfamily
- protein binding
- DEAD-like helicases superfamily
- Helicase conserved C-terminal domain
- single-stranded RNA binding
- P-loop containing Nucleoside Triphosphate Hydrolases
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intermediate filament cytoskeleton
- cytosol