Sobp Gene Summary [Mouse]
Enables SUMO polymer binding activity. Involved in cochlea development. Acts upstream of or within inner ear morphogenesis; locomotory behavior; and sensory perception of sound. Located in nucleus. Is expressed in several structures, including brain; cranial ganglion; genitourinary system; immune system; and inner ear. Orthologous to human SOBP (sine oculis binding protein homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sobp |
| Official Name | sine oculis binding protein [Source:MGI Symbol;Acc:MGI:1924427] |
| Ensembl ID | ENSMUSG00000038248 |
| Bio databases IDs | |
| Aliases | sine oculis binding protein |
| Synonyms | 2900009C16RIK, 5330439J01Rik, FLJ10159, jc, jcx1, JXC1, MRAMS, RGD1560479, sine oculis binding protein, sine oculis binding protein homolog, Sobpl |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sobp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Sine oculis-binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- metastasis
- schizophrenia
- syndromic mental retardation
- bladder cancer
- pemphigus foliaceus
- mental retardation, anterior maxillary protrusion, and strabismus
- systemic lupus erythematosus
- overall survival
regulates
role in cell
- proliferation
- expression in
- migration
- invasion by
- glycolysis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sobp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of sound
- locomotory behavior
- cognition
- cochlea development
- inner ear morphogenesis
- organ development
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- SUMO polymer binding